9th Symposium 2023

Event Detail

November 30, 2023 9:00 am
December 2, 2023 9:00 pm
28-34 Athanasiou Diakou Str. 117 43, Athens, Greece

Organizers

SCEP
info@scep.gr
00302107240039
https://scep.gr
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The 9th Symposium “Advances in Cancer Immunology & Immunotherapy is an intensive”, three days interactive meeting during which all invited speakers will address the accumulated knowledge so far from the field of translational cancer research, clinical cancer research and clinical trials based on immunotherapy-guided strategies.

The scientific objectives of this program are focused on (a) biomarkers for predicting response to immunotherapeutic modalities in cancer management; (b) mechanisms of action for immunotherapeutic treatments in the treatment of malignancy; (c) data from clinical trials investigating the efficacy and safety of cancer immunotherapy regimens; and (d) strategies for immunomodulation, counteracting resistance and mitigating adverse events.

This year’s Conference will feature world-renowned oncologists and researchers who will provide their insights on the topics above in an effort to better understand tumor evolution and designing improved treatment strategies. Our Meeting will welcome scientists, clinicians, students and health care professionals interested in the field of Cancer Immunology and Immunotherapy to participate.

The Organizing Committee

Athanasios Kotsakis
MD, PhD, Professor of Medical Oncology, School of Medicine, University of Thessaly, Larissa , Greece

Constantin N. Baxevanis
Scientific Director, Cancer Immunology and Immunotherapy Center “St.Savvas” Cancer Hospital, Athens, Greece

Sophia Karagiannis
Professor of Translational Cancer Immunology and Immunotherapy

Jörg Wischhusen 
Professor of Experimental Tumor Immunology University of Würzburg School of Medicine Department of Gynecology and Obstetrics, Germany

    Opening:Organizing Committee
    08.50 - 09.00
    Session 1: Antitumor Immunity and Immunomodulation in the tumor microenvironment (part I)

    Chairs: C.N. Baxevanis (GR), J. Wischhusen (DE)

    • Viktor Umansky
    Immunosuppression in tumor Microenvironment and its targeting
    09.00 - 09.20
    • Noel de Miranda
    Insights into colorectal cancer immunity revealed by multidimensional spatial approaches
    09.20 - 09.40
    • Maria Tsoumakidou
    Interferon-induced lysosomal membrane permeabilization causes cDC1-deserts in tumors
    09.40 - 10.00
    MD, Ph.D., Group Leader Institute of Bioinnovation BSRC Fleming
    Discussion
    10.00 - 10.10
    Coffee Break
    10.10 - 10.40
    Session 2: Antitumor Immunity and Immunomodulation in the tumor microenvironment (part II)

    Chairs: J. Wischhusen (DE), V. Georgoulias (GR)

    • Anastasia Xagara
    Pre-existing immunity in non-small cell lung cancer
    10.40 - 11.00
    Postdoctoral Researcher at Laboratory of Oncology, Medical School of Thessaly, Larisa
    • Vincenzo Bronte
    The cold immune environment in pancreatic cancer
    11.00 - 11.20
    • Océane CB Martin
    Microbiota-gut-brain axis in glioblastoma development
    11.20 - 11.40
    Associate Professor Université de Bordeaux
    • Teresa Frisan
    Immuno-microenvironment in infection and cancer
    11.40 - 12.00
    PhD, Professor in Cell and Molecular Biology at Umeå University
    Discussion
    12.00 - 12.15
    • Teresa Whiteside
    Keynote lecture
    12.15 - 12.45

    Chairs: A. Kotsakis (GR), O.E. Tsitsilonis (GR)

    Tumor-derived exosomes in plasma of cancer patients induce stress and death in immune cells: danger from within

    Professor, Department of Immunology, University of Pittsburgh
    Light Lunch
    12.45 - 14.00
      Short Presentations

      Chairs: I. Pateras (GR), O. Martin (FR)

      T Cell Receptor And Immune Response Gene Studies In Tumor Microenvironment And Peripheral Blood In Head And Neck Cancer Patients (Panagiota Batsaki)
      14.00 - 14.15
      The Tcr Vβ Repertoire Composition As A Predictive Biomarker OfImmunotherapy Efficiency In Non Small Cell Lung Cancer Patients (Panagiota Batsaki)
      14.15 - 14.30
      KMT2C Is A Tumor Suppressor In Bladder Cancer And Its Loss Leads To Favorable Response To Immunotherapy (Fotini E. Koukouzeli)
      14.30 - 14.45
      Real-World Data OnImmunotherapy In Patients With Soft Tissue Sarcoma A Study From The Hellenic Group Of Sarcoma And Rare Cancers (Eleni Georgaki)
      14.45 - 15.00
      Session 3: Novel anticancer therapies (Part I)

      Chairs: C.N. Baxevanis (GR), V. Umansky (DE)

      • Else Marit Inderberg
      CAR- and TCR-based therapy in solid cancers
      15.00 - 15.20
      Senior Scientist; PhD, Group leader & Head of Immunomonitoring
      • Alejandro Madrigal
      The power of novel allogeneic CAR-T cell to treat malignant disorders
      15.20 - 15.40
      • Jörg Wischhusen
      Tolerogenic onco-fetal proteins as emerging targets for novel therapies
      15.40 - 16.00
      Professor of Experimental Tumor Immunology University of Würzburg School of Medicine Department of Gynecology and Obstetrics
      Discussion
      16.00 - 16.10
      Coffee Break
      16.10 - 16.30
      • Graham Peter Pawelec
      Keynote lecture
      16.30 - 17.00

      Chairs: C.N. Baxevanis (GR), J. Wischhusen (DE)

      Peripheral blood biomarkers predicting clinical response to checkpoint blockade in melanoma

      Professor of Experimental Immunology, Center of Medical Research, Department of Immunology, University of Tuebingen
      • Apostolos Laskarakis
      Educational lecture
      17.00 - 17.20

      Chairs: A. Kotsakis (GR), G. Pawelec (DE)

      Immunotherapy in melanoma: past-present-future

      Director of Oncology Department at Athens Medical Group
      Interactive session with the Speakers from sessions 1-3
      17.20 - 19.00
      Session 4: Cancer Biomarkers (Part I)

      Chairs: S. Karagiannis (UK), E. M. Inderberg (NO)

      • Maria Goulielmaki
      The biomarker utility of TCR repertoire for clinical responses to immunotherapy in NSCLC
      09.00 - 09.20
      Postdoctoral Researcher at Cancer Immunology and Immunotherapy Center, Athens
      • Alexios Matikas
      Dissecting the tumor microenvironment in early breast cancer: clinical implications and novel insights
      09.20 - 09.40
      • Ioannis S. Pateras
      Immune-based biomarkers in solid tumors
      09.40 - 10.00
      Associate Professor, 2nd Department of Pathology, "Attikon" University Hospital, Medical School, National and Kapodistrian University of Athens, Greece.
      Discussion
      10.00 - 10.10
      Coffee Break
      10.10 - 10.40
      Session 5: Novel anticancer therapies (part II)

      Chairs: B. Seliger (DE), T. Frisan (SE)

      • Panagiotis Verginis
      Therapeutic targeting of Treg cells in cancer
      10.40 - 11.00
      IMBB Group Leader (Associate Professor, Medical School, Univ. of Crete)
        Fine-tuning antigen presentation for cancer immunotherapy
        11.00 - 11.20
        • Sophia Karagiannis
        Immunotherapy for cancer via reprogramming macrophages with IgE antibody
        11.20 - 11.40
        Professor of Translational Cancer Immunology and Immunotherapy, St. John’s Institute of Dermatology, School of Basic & Medical Biosciences, King’s College London
        Discussion
        11.40 - 11.50
        • Michael Koukourakis
        Educational lecture (Sponsored by Astra Zeneca)
        11.50 - 12.10

        Chairs: A. Kotsakis (GR), V. Georgoulias (GR)

        Combining radiotherapy and immunotherapy

        Professor of Radiation Oncology, Medical School, Democritus University of Thrace, Alexandroupolis
        Light Lunch
        12.10 - 13.30
        Short Presentations

        Chairs: S. Karagiannis (UK), A. Chatzigeorgiou (GR)

        Characterization Of A B-Like Phenotype Cell FoundIn Colon Adenocarcinomas (Adrien Noa-Bolaño)
        13.30 - 13.45
        The Immune Status Of Colorectal Cancer Patients Reveals A Deep ImpairmentIn Relevant Cellular Effectors Of The Immune System (Udo Rahner)
        13.45 - 14.00
        Assessing The Behaviour Of The Genotoxin Producing Salmonella EntericaIn Pro Carcinogenic Mouse Models (María López Chiloeches)
        14.00 - 14.15
        Microenvironmental Conditions And Hla ClassI Expression Of Breast Cancer (Erasmia Xanthopoulou)
        14.15 - 14.30
        Neoadjuvant Chemoradiotherapy Of Rectal Cancer And HLA-Class-I-Related Molecules Expression (Ioannis M Koukourakis)
        14.30 - 14.45
        GDF-15 – A Cytokine And Its Immunomodulatory Potential (Beatrice Haack)
        14.45 - 15.00
        Session 6: Cancer Biomarkers (II)

        Chairs: C.N. Baxevanis (GR), S. Karagiannis (UK)

        • Vivian Tseveleki
        T cell therapy in lung cancer
        15.00 - 15.20
        • Han Suk Ryu
        High throughput proteomics for the detection of cancer biomarkers
        15.20 - 15.40
        Associate Professor Pathology, SNUCM Pathology, SNUH Pathology
        • Paul Victor Lehmann
        ImmunoSpot assays permit B cell affinity measurements
        15.40 - 16.00
        Discussion
        16.00 - 16.10
        Coffee
        16.10 - 16.40
        • Barbara Seliger
        Keynote lecture
        16.40 - 17.10

        Chairs: J. Wischhusen (DE), A. Psyrri (GR)

        Oncogenes and tumor suppressor genes as regulators for immune surveillance

        Prof. Dr., Martin-Luther-Universität Halle-Wittenberg Institut für Medizinische Immunologie
        • Amanda Psyrri
        Educational lecture
        17.10 - 17.30

        Chairs: A. Kotsakis (GR), T. Whiteside (US)

        Head and neck cancer: past, present, future

        Professor of Medical Oncology, Chairman of Internal Medicine and Chief of Medical Oncology, Attikon University Hospital, Athens
        Interactive session with the Speakers from sessions 4-6
        17.30 – 19.30
        Session 7: New topics in cancer immunology and immunotherapy

        Chairs: S. Karagiannis (UK), N. de Miranda (NL)

        • Daniel Öhlund
        Onco-fibrotherapy in pancreatic cancer. Can the Cancer wound heal?
        9.00 - 9.20
        M.D, Ph.D., Assistant Professor and Consultant Oncologist Wallenberg Molecular Medicine Fellow
        • Sofia Tsoka
        Bio-informatic analysis in cancer immunology and immunotherapy
        9.20 - 9.40
        Reader in Bioinformatics, King's College London
        • Laura Soucek
        Progress in the development of a clinically viable MYC inhibitor
        9.40 - 10.00
        ICREA Research Professor at VHIO, CEO and co-founder of Peptomyc S.L.
        • Apostolos Klinakis
        Epigenetic regulation in cancer
        10.00 - 10.20
        PhD, Investigator - Professor Level
        Discussion
        10.20 - 10.35
        Coffee Break
        10.35 - 11.00
        Session 8: Immunotherapies alone or in combination with other therapies (Part I)

        Chairs: A. Kotsakis (GR), A. Klinakis (GR)

        • Evangelos Georgios Fergadis
        Emerging standards in the perio-operative treatment in NSCLC
        11.00 - 11.20
        • Dionysios Papadatos - Pastos
        State of the art of immunotherapy in the first line setting in NSCLC
        11.20 - 11.40
        • Alexios Strimpakos
        The role of immunotherapy in gastric and gastroesophangeal cancer
        11.40 - 12.00
        MD, Medical Oncologist, HYGEIA Hospital
        Discussion
        12.00 - 12.10
        Lunch
        12.10 - 13.30
        Short Presentations

        Chairs: J. Wischhusen (DE), A. Xagara (GR)

        Prognostic Significance Of SHP2 ExpressionIn Non Small Lung Cancer Patients (Eleni A Karatrasoglou)
        13.30 - 13.45
        Concomitant Causes Of AnaemiaIn A Patient With Lung Adenocarcinoma Under anti-Pd-1 Immunotherapy (Aleksandros Patsouras)
        13.45 - 14.00
        Distinct Profile Of Proliferating CD8+/Tcf1+T Cells Among Different Breast Cancer Molecular Subtypes (Konstantinos Ntostoglou)
        14.00 - 14.15
        Fc Engineered Monoclonal Antibodies for Triple Negative Breast Cancer Therapy (Alicia Chenoweth)
        14.15 - 14.30
        Effect Of The MEK Inhibitor Cobimetinib On BRAF V600E Mutated Thyroid Carcinoma (Mario Udinotti)
        14.30 - 14.45
        Session 9: Immunotherapies alone or in combination with other therapies (Part II)

        Chairs: J. Wischhusen (DE), F. Dimitrakopoulos (GR)

        • Konstantinos Trifonidis
        Immunotherapy in breast cancer
        15.00 - 15.20
        • Petros Tsantoulis
        Immunotherapy in urothelial carcinomas
        15.20 - 15.40
        Discussion
        15.40 - 16.00
        Coffee Break
        16.00 - 16.30
        • Valsamo Anagnostou
        Keynote lecture
        16.30 - 17.00

        Chairs: A. Kotsakis (GR), V. Georgoulias (GR)

        Persistent Mutation Burden Drives Sustained Anti-tumor Immune Response

        M.D., Ph.D., Associate Professor of Oncology | Johns Hopkins Medicine
        Abstract Awards: Organizing Committee
        17.00 - 17.10
        Interactive session with the Speakers from sessions 7-9
        17.10 – 19.10
        Concluding remarks
        19.10 - 19.25